@prefix fhir: <http://hl7.org/fhir/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .

# - resource -------------------------------------------------------------------

[] a fhir:CodeSystem ;
  fhir:id [ fhir:v "v3-substanceAdminSubstitution"] ;
  fhir:language [ fhir:v "en"] ;
  fhir:text [
     fhir:status [ fhir:v "generated" ]
  ] ;
  fhir:url [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution"], [ fhir:v "http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution"] ;
  fhir:identifier ( [
     fhir:system [ fhir:v "urn:ietf:rfc:3986" ] ;
     fhir:value [ fhir:v "urn:oid:2.16.840.1.113883.5.1070" ]
  ] [
     fhir:system [ fhir:v "urn:ietf:rfc:3986" ] ;
     fhir:value [ fhir:v "urn:oid:2.16.840.1.113883.5.1070" ]
  ] ) ;
  fhir:version [ fhir:v "3.0.0"], [ fhir:v "3.0.0"] ;
  fhir:name [ fhir:v "SubstanceAdminSubstitution"], [ fhir:v "SubstanceAdminSubstitution"] ;
  fhir:title [ fhir:v "Substance Admin Substitution"], [ fhir:v "Substance Admin Substitution"] ;
  fhir:status [ fhir:v "active"], [ fhir:v "active"] ;
  fhir:experimental [ fhir:v "false"], [ fhir:v "false"] ;
  fhir:date [ fhir:v "2019-03-20"], [ fhir:v "2019-03-20"] ;
  fhir:publisher [ fhir:v "Health Level Seven International"], [ fhir:v "Health Level Seven International"] ;
  fhir:contact ( [
     fhir:telecom ( [
       fhir:system [ fhir:v "url" ] ;
       fhir:value [ fhir:v "http://hl7.org" ]
     ] [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "hq@HL7.org" ]
     ] )
  ] [
     fhir:telecom ( [
       fhir:system [ fhir:v "url" ] ;
       fhir:value [ fhir:v "http://hl7.org" ]
     ] [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "hq@HL7.org" ]
     ] )
  ] ) ;
  fhir:description [ fhir:v "Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided."], [ fhir:v "Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided."] ;
  fhir:copyright [ fhir:v "This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html"], [ fhir:v "This material derives from the HL7 Terminology THO. THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html"] ;
  fhir:caseSensitive [ fhir:v "true"] ;
  fhir:hierarchyMeaning [ fhir:v "is-a"] ;
  fhir:content [ fhir:v "complete"] ;
  fhir:property ( [
     fhir:extension ( [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry" ] ;
       fhir:value [ fhir:v "antisymmetric" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity" ] ;
       fhir:value [ fhir:v "transitive" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity" ] ;
       fhir:value [ fhir:v "irreflexive" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable" ] ;
       fhir:value [ fhir:v "true" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind" ] ;
       fhir:value [ fhir:v "Specializes" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName" ] ;
       fhir:value [ fhir:v "Generalizes" ]
     ] ) ;
     fhir:code [ fhir:v "Specializes" ] ;
     fhir:description [ fhir:v "The child code is a more narrow version of the concept represented by the parent code.  I.e. Every child concept is also a valid parent concept.  Used to allow determination of subsumption.  Must be transitive, irreflexive, antisymmetric." ] ;
     fhir:type [ fhir:v "Coding" ]
  ] [
     fhir:extension ( [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-symmetry" ] ;
       fhir:value [ fhir:v "antisymmetric" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-transitivity" ] ;
       fhir:value [ fhir:v "transitive" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-reflexivity" ] ;
       fhir:value [ fhir:v "irreflexive" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-isNavigable" ] ;
       fhir:value [ fhir:v "true" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-relationshipKind" ] ;
       fhir:value [ fhir:v "Generalizes" ]
     ] [
       fhir:url [ fhir:v "http://terminology.hl7.org/StructureDefinition/ext-mif-relationship-inverseName" ] ;
       fhir:value [ fhir:v "Specializes" ]
     ] ) ;
     fhir:code [ fhir:v "Generalizes" ] ;
     fhir:description [ fhir:v "Inverse of Specializes.  Only included as a derived relationship." ] ;
     fhir:type [ fhir:v "Coding" ]
  ] [
     fhir:code [ fhir:v "internalId" ] ;
     fhir:uri [ fhir:v "http://terminology.hl7.org/CodeSystem/utg-concept-properties#v3-internal-id" ] ;
     fhir:description [ fhir:v "The internal identifier for the concept in the HL7 Access database repository." ] ;
     fhir:type [ fhir:v "code" ]
  ] [
     fhir:code [ fhir:v "notSelectable" ] ;
     fhir:uri [ fhir:v "http://hl7.org/fhir/concept-properties#notSelectable" ] ;
     fhir:description [ fhir:v "Indicates that the code is abstract - only intended to be used as a selector for other concepts" ] ;
     fhir:type [ fhir:v "boolean" ]
  ] [
     fhir:code [ fhir:v "status" ] ;
     fhir:uri [ fhir:v "http://hl7.org/fhir/concept-properties#status" ] ;
     fhir:description [ fhir:v "Designation of a concept's state. Normally is not populated unless the state is retired." ] ;
     fhir:type [ fhir:v "code" ]
  ] ) ;
  fhir:concept ( [
     fhir:code [ fhir:v "_ActSubstanceAdminSubstitutionCode" ] ;
     fhir:display [ fhir:v "ActSubstanceAdminSubstitutionCode" ] ;
     fhir:definition [ fhir:v "Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects." ] ;
     fhir:designation ( [
       fhir:language [ fhir:v "en" ] ;
       fhir:use [
         fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
         fhir:code [ fhir:v "display" ]
       ] ;
       fhir:value [ fhir:v "ActSubstanceAdminSubstitutionCode" ]
     ] ) ;
     fhir:property ( [
       fhir:code [ fhir:v "notSelectable" ] ;
       fhir:value [ fhir:v "true" ]
     ] [
       fhir:code [ fhir:v "status" ] ;
       fhir:value [ fhir:v "active" ]
     ] [
       fhir:code [ fhir:v "internalId" ] ;
       fhir:value [ fhir:v "21284" ]
     ] ) ;
     fhir:concept ( [
       fhir:code [ fhir:v "E" ] ;
       fhir:display [ fhir:v "equivalent" ] ;
       fhir:definition [ fhir:v "Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product." ] ;
       fhir:designation ( [
         fhir:language [ fhir:v "en" ] ;
         fhir:use [
           fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
           fhir:code [ fhir:v "display" ]
         ] ;
         fhir:value [ fhir:v "equivalent" ]
       ] ) ;
       fhir:property ( [
         fhir:code [ fhir:v "status" ] ;
         fhir:value [ fhir:v "active" ]
       ] [
         fhir:code [ fhir:v "internalId" ] ;
         fhir:value [ fhir:v "23107" ]
       ] ) ;
       fhir:concept ( [
         fhir:code [ fhir:v "EC" ] ;
         fhir:display [ fhir:v "equivalent composition" ] ;
         fhir:definition [ fhir:v "Substitution occurred or is permitted with another product that is a:\r\n\r\n *  pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester\r\n *  pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration\r\n\r\n*Examples:* \r\n\r\n *  *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate\r\n *  *Pharmaceutical equivalent:* Lisonpril for Zestril" ] ;
         fhir:designation ( [
           fhir:language [ fhir:v "en" ] ;
           fhir:use [
             fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
             fhir:code [ fhir:v "display" ]
           ] ;
           fhir:value [ fhir:v "equivalent composition" ]
         ] ) ;
         fhir:property ( [
           fhir:code [ fhir:v "status" ] ;
           fhir:value [ fhir:v "active" ]
         ] [
           fhir:code [ fhir:v "internalId" ] ;
           fhir:value [ fhir:v "23108" ]
         ] ) ;
         fhir:concept ( [
           fhir:code [ fhir:v "BC" ] ;
           fhir:display [ fhir:v "brand composition" ] ;
           fhir:definition [ fhir:v "Substitution occurred or is permitted between equivalent Brands but not Generics\r\n\r\n*Examples:* \r\n\r\n *  Zestril for Prinivil\r\n *  Coumadin for Jantoven" ] ;
           fhir:designation ( [
             fhir:language [ fhir:v "en" ] ;
             fhir:use [
               fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
               fhir:code [ fhir:v "display" ]
             ] ;
             fhir:value [ fhir:v "brand composition" ]
           ] ) ;
           fhir:property ( [
             fhir:code [ fhir:v "status" ] ;
             fhir:value [ fhir:v "active" ]
           ] [
             fhir:code [ fhir:v "internalId" ] ;
             fhir:value [ fhir:v "23109" ]
           ] )
         ] [
           fhir:code [ fhir:v "G" ] ;
           fhir:display [ fhir:v "generic composition" ] ;
           fhir:definition [ fhir:v "Substitution occurred or is permitted between equivalent Generics but not Brands\r\n\r\n*Examples:* \r\n\r\n *  Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)" ] ;
           fhir:designation ( [
             fhir:language [ fhir:v "en" ] ;
             fhir:use [
               fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
               fhir:code [ fhir:v "display" ]
             ] ;
             fhir:value [ fhir:v "generic composition" ]
           ] [
             fhir:language [ fhir:v "en" ] ;
             fhir:use [
               fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
               fhir:code [ fhir:v "display" ]
             ] ;
             fhir:value [ fhir:v "generic composition" ]
           ] ) ;
           fhir:property ( [
             fhir:code [ fhir:v "status" ] ;
             fhir:value [ fhir:v "active" ]
           ] [
             fhir:code [ fhir:v "internalId" ] ;
             fhir:value [ fhir:v "16623" ]
           ] )
         ] )
       ] [
         fhir:code [ fhir:v "TE" ] ;
         fhir:display [ fhir:v "therapeutic alternative" ] ;
         fhir:definition [ fhir:v "Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.\r\n\r\n*Examples:* \r\n\r\n *  ranitidine for Tagamet" ] ;
         fhir:designation ( [
           fhir:language [ fhir:v "en" ] ;
           fhir:use [
             fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
             fhir:code [ fhir:v "display" ]
           ] ;
           fhir:value [ fhir:v "therapeutic alternative" ]
         ] ) ;
         fhir:property ( [
           fhir:code [ fhir:v "status" ] ;
           fhir:value [ fhir:v "active" ]
         ] [
           fhir:code [ fhir:v "internalId" ] ;
           fhir:value [ fhir:v "16624" ]
         ] ) ;
         fhir:concept ( [
           fhir:code [ fhir:v "TB" ] ;
           fhir:display [ fhir:v "therapeutic brand" ] ;
           fhir:definition [ fhir:v "Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n *  Zantac for Tagamet" ] ;
           fhir:designation ( [
             fhir:language [ fhir:v "en" ] ;
             fhir:use [
               fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
               fhir:code [ fhir:v "display" ]
             ] ;
             fhir:value [ fhir:v "therapeutic brand" ]
           ] ) ;
           fhir:property ( [
             fhir:code [ fhir:v "status" ] ;
             fhir:value [ fhir:v "active" ]
           ] [
             fhir:code [ fhir:v "internalId" ] ;
             fhir:value [ fhir:v "23105" ]
           ] )
         ] [
           fhir:code [ fhir:v "TG" ] ;
           fhir:display [ fhir:v "therapeutic generic" ] ;
           fhir:definition [ fhir:v "Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands\r\n\r\n>\r\n\r\n*Examples:* \r\n\r\n *  Ranitidine for cimetidine" ] ;
           fhir:designation ( [
             fhir:language [ fhir:v "en" ] ;
             fhir:use [
               fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
               fhir:code [ fhir:v "display" ]
             ] ;
             fhir:value [ fhir:v "therapeutic generic" ]
           ] ) ;
           fhir:property ( [
             fhir:code [ fhir:v "status" ] ;
             fhir:value [ fhir:v "active" ]
           ] [
             fhir:code [ fhir:v "internalId" ] ;
             fhir:value [ fhir:v "23106" ]
           ] )
         ] )
       ] )
     ] [
       fhir:code [ fhir:v "F" ] ;
       fhir:display [ fhir:v "formulary" ] ;
       fhir:definition [ fhir:v "This substitution was performed or is permitted based on formulary guidelines." ] ;
       fhir:designation ( [
         fhir:language [ fhir:v "en" ] ;
         fhir:use [
           fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
           fhir:code [ fhir:v "display" ]
         ] ;
         fhir:value [ fhir:v "formulary" ]
       ] ) ;
       fhir:property ( [
         fhir:code [ fhir:v "status" ] ;
         fhir:value [ fhir:v "active" ]
       ] [
         fhir:code [ fhir:v "internalId" ] ;
         fhir:value [ fhir:v "16625" ]
       ] )
     ] [
       fhir:code [ fhir:v "N" ] ;
       fhir:display [ fhir:v "none" ] ;
       fhir:definition [ fhir:v "No substitution occurred or is permitted." ] ;
       fhir:designation ( [
         fhir:language [ fhir:v "en" ] ;
         fhir:use [
           fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/designation-usage" ] ;
           fhir:code [ fhir:v "display" ]
         ] ;
         fhir:value [ fhir:v "none" ]
       ] ) ;
       fhir:property ( [
         fhir:code [ fhir:v "status" ] ;
         fhir:value [ fhir:v "active" ]
       ] [
         fhir:code [ fhir:v "internalId" ] ;
         fhir:value [ fhir:v "16622" ]
       ] )
     ] )
  ] ) .

# -------------------------------------------------------------------------------------

