<?xml version="1.0" encoding="UTF-8"?><CodeSystem xmlns="http://hl7.org/fhir"><id value="certainty-subcomponent-type"/><meta><lastUpdated value="2020-04-09T21:10:28.568+00:00"/></meta><text><status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: CodeSystem certainty-subcomponent-type</b></p><a name="certainty-subcomponent-type"> </a><a name="hccertainty-subcomponent-type"> </a><a name="certainty-subcomponent-type-en-US"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Last updated: 2020-04-09 21:10:28+0000</p></div><p>This case-sensitive code system <code>http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type</code> defines the following codes:</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style="white-space:nowrap">RiskOfBias<a name="certainty-subcomponent-type-RiskOfBias"> </a></td><td>Risk of bias</td><td>methodologic concerns reducing internal validity.</td></tr><tr><td style="white-space:nowrap">Inconsistency<a name="certainty-subcomponent-type-Inconsistency"> </a></td><td>Inconsistency</td><td>concerns that findings are not similar enough to support certainty.</td></tr><tr><td style="white-space:nowrap">Indirectness<a name="certainty-subcomponent-type-Indirectness"> </a></td><td>Indirectness</td><td>concerns reducing external validity.</td></tr><tr><td style="white-space:nowrap">Imprecision<a name="certainty-subcomponent-type-Imprecision"> </a></td><td>Imprecision</td><td>fuzzy or wide variability.</td></tr><tr><td style="white-space:nowrap">PublicationBias<a name="certainty-subcomponent-type-PublicationBias"> </a></td><td>Publication bias</td><td>likelihood that what is published misrepresents what is available to publish.</td></tr><tr><td style="white-space:nowrap">DoseResponseGradient<a name="certainty-subcomponent-type-DoseResponseGradient"> </a></td><td>Dose response gradient</td><td>higher certainty due to dose response relationship.</td></tr><tr><td style="white-space:nowrap">PlausibleConfounding<a name="certainty-subcomponent-type-PlausibleConfounding"> </a></td><td>Plausible confounding</td><td>higher certainty due to risk of bias in opposite direction.</td></tr><tr><td style="white-space:nowrap">LargeEffect<a name="certainty-subcomponent-type-LargeEffect"> </a></td><td>Large effect</td><td>higher certainty due to large effect size.</td></tr></table></div></text><url value="http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type"/><identifier><system value="urn:ietf:rfc:3986"/><value value="urn:oid:2.16.840.1.113883.4.642.1.1360"/></identifier><version value="1.0.0"/><name value="StatisticCertaintySubcomponentType"/><title value="StatisticCertaintySubcomponentType"/><status value="draft"/><experimental value="false"/><date value="2020-04-09T21:10:28+00:00"/><publisher value="Health Level Seven International"/><contact><telecom><system value="url"/><value value="http://hl7.org"/></telecom><telecom><system value="email"/><value value="hq@HL7.org"/></telecom></contact><description value="The subcomponent classification of quality of evidence rating systems."/><copyright value="This material derives from the HL7 Terminology (THO). THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license.html"/><caseSensitive value="true"/><valueSet value="http://terminology.hl7.org/ValueSet/certainty-subcomponent-type"/><content value="complete"/><concept><code value="RiskOfBias"/><display value="Risk of bias"/><definition value="methodologic concerns reducing internal validity."/></concept><concept><code value="Inconsistency"/><display value="Inconsistency"/><definition value="concerns that findings are not similar enough to support certainty."/></concept><concept><code value="Indirectness"/><display value="Indirectness"/><definition value="concerns reducing external validity."/></concept><concept><code value="Imprecision"/><display value="Imprecision"/><definition value="fuzzy or wide variability."/></concept><concept><code value="PublicationBias"/><display value="Publication bias"/><definition value="likelihood that what is published misrepresents what is available to publish."/></concept><concept><code value="DoseResponseGradient"/><display value="Dose response gradient"/><definition value="higher certainty due to dose response relationship."/></concept><concept><code value="PlausibleConfounding"/><display value="Plausible confounding"/><definition value="higher certainty due to risk of bias in opposite direction."/></concept><concept><code value="LargeEffect"/><display value="Large effect"/><definition value="higher certainty due to large effect size."/></concept></CodeSystem>