v3-lrg
type: NamingSystem
node role: treeRoot
id:
  v: v3-lrg
text:
  status:
    v: generated
  div: Generated Narrative: NamingSystem v3-lrg Summary Defining URL http://terminology.hl7.org/NamingSystem/v3-lrg Version 2.1.0 Name Lrg Title Locus Reference Genomic Sequences (LRG) Status retired Definition In collaboration with NCBI, the European Bioinformatics Institute (EBI) is developing the Locus Reference Genomic Sequences (LRG) database, which is a database of reference sequences. LRG is a system for providing a genomic DNA sequence representation of a single gene that is idealized, has a permanent ID (with no versioning), and core content that never changes. LRG is not a nomenclature system. More than one LRG could be created for a region of interest, should that need arise. Additional annotations will be present that may change with time (each item carrying its own date stamp), so that the latest ancillary knowledge about a gene is directly available. In other words, an LRG sequence and its core annotation are not meant to represent current biology knowledge, but to provide a standard for reporting variation in a stable coordinate system. The combination of the LRG plus the updatable-annotation layer will be used to support the biological interpretation of variants. LRG identifiers can be used with the HL7 coded data type (code data type that accepts expression data, or a coded expression data type). This coded data type will be gene symbols can be used with the HL7 coded data type. For example, in the HL7 messages specified according to the HL7 V2 Clinical Genomics Fully LOINC-Qualified Genetic Variation Model, LRG identifiers can be used to as the observation values for Genomic Reference Sequence Identifier (LOINC code: 48013-7). LRG is a database that can be used freely by the public. Publisher HL7 Identifiers Type Value Preferred OID 2.16.840.1.113883.6.283 true URI http://www.lrg-sequence.org true
extension:
  url:
    v: http://hl7.org/fhir/5.0/StructureDefinition/extension-NamingSystem.url
  value:
    v: http://terminology.hl7.org/NamingSystem/v3-lrg
extension:
  url:
    v: http://hl7.org/fhir/5.0/StructureDefinition/extension-NamingSystem.version
  value:
    v: 2.1.0
extension:
  url:
    v: http://hl7.org/fhir/5.0/StructureDefinition/extension-NamingSystem.title
  value:
    v: Locus Reference Genomic Sequences (LRG)
name:
  v: Lrg
status:
  v: retired
kind:
  v: codesystem
date:
  v: 2021-11-09T10:00:00+10:00
publisher:
  v: HL7
contact:
  name:
    v: Wellcome Trust
responsible:
  v: HL7
description:
  v: In collaboration with NCBI, the European Bioinformatics Institute (EBI) is developing the Locus Reference Genomic Sequences (LRG) database, which is a database of reference sequences. LRG is a system for providing a genomic DNA sequence representation of a single gene that is idealized, has a permanent ID (with no versioning), and core content that never changes. LRG is not a nomenclature system. More than one LRG could be created for a region of interest, should that need arise. Additional annotations will be present that may change with time (each item carrying its own date stamp), so that the latest ancillary knowledge about a gene is directly available. In other words, an LRG sequence and its core annotation are not meant to represent current biology knowledge, but to provide a standard for reporting variation in a stable coordinate system. The combination of the LRG plus the updatable-annotation layer will be used to support the biological interpretation of variants. LRG identifiers can be used with the HL7 coded data type (code data type that accepts expression data, or a coded expression data type). This coded data type will be gene symbols can be used with the HL7 coded data type. For example, in the HL7 messages specified according to the HL7 V2 Clinical Genomics Fully LOINC-Qualified Genetic Variation Model, LRG identifiers can be used to as the observation values for Genomic Reference Sequence Identifier (LOINC code: 48013-7). LRG is a database that can be used freely by the public.
unique id:
  type:
    v: oid
  value:
    v: 2.16.840.1.113883.6.283
  preferred:
    v: true
unique id:
  type:
    v: uri
  value:
    v: http://www.lrg-sequence.org
  preferred:
    v: true