<?xml version="1.0" encoding="UTF-8"?>

<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="adverse-event-causality-assess"/>
  <meta>
    <lastUpdated value="2020-04-09T21:10:28.568+00:00"/>
  </meta>
  <text>
    <status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><p>This case-sensitive code system <code>http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess</code> defines the following codes:</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style="white-space:nowrap">certain<a name="adverse-event-causality-assess-certain"> </a></td><td>Certain</td><td>i) Event or laboratory test abnormality, with plausible time relationship to drug intake; ii) Cannot be explained by disease or other drugs; iii) Response to withdrawal plausible (pharmacologically, pathologically); iv) Event definitive pharmacologically or phenomenologically (i.e. an objective and specific medical disorder or a recognized pharmacological phenomenon); or v) Re-challenge satisfactory, if necessary.</td></tr><tr><td style="white-space:nowrap">probably-likely<a name="adverse-event-causality-assess-probably-likely"> </a></td><td>Probably/Likely</td><td>i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Unlikely to be attributed to disease or other drugs; iii) Response to withdrawal clinically reasonable; or iv) Re-challenge not required.</td></tr><tr><td style="white-space:nowrap">possible<a name="adverse-event-causality-assess-possible"> </a></td><td>Possible</td><td>i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Could also be explained by disease or other drugs; or iii) Information on drug withdrawal may be lacking or unclear.</td></tr><tr><td style="white-space:nowrap">unlikely<a name="adverse-event-causality-assess-unlikely"> </a></td><td>Unlikely</td><td>i) Event or laboratory test abnormality, with a time to drug intake that makes a relationship improbable (but not impossible); or ii) Disease or other drugs provide plausible explanations.</td></tr><tr><td style="white-space:nowrap">conditional-classified<a name="adverse-event-causality-assess-conditional-classified"> </a></td><td>Conditional/Classified</td><td>i) Event or laboratory test abnormality; ii) More data for proper assessment needed; or iii) Additional data under examination.</td></tr><tr><td style="white-space:nowrap">unassessable-unclassifiable<a name="adverse-event-causality-assess-unassessable-unclassifiable"> </a></td><td>Unassessable/Unclassifiable</td><td>i) Report suggesting an adverse reaction; ii) Cannot be judged because information is insufficient or contradictory; or iii) Data cannot be supplemented or verified.</td></tr></table></div>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="pc"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="1"/>
  </extension>
  <url value="http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess"/>
  <identifier>
    <system value="urn:ietf:rfc:3986"/>
    <value value="urn:oid:2.16.840.1.113883.4.642.1.1254"/>
  </identifier>
  <version value="1.0.0"/>
  <name value="AdverseEventCausalityAssessment"/>
  <title value="AdverseEventCausalityAssessment"/>
  <status value="draft"/>
  <experimental value="false"/>
  <date value="2020-04-09T21:10:28+00:00"/>
  <publisher value="Health Level Seven International"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="hq@HL7.org"/>
    </telecom>
  </contact>
  <description value="Codes for the assessment of whether the entity caused the event."/>
  <copyright value="This material derives from the HL7 Terminology (THO). THO is copyright ©1989+ Health Level Seven International and is made available under the CC0 designation. For more licensing information see: https://terminology.hl7.org/license"/>
  <caseSensitive value="true"/>
  <valueSet value="http://terminology.hl7.org/ValueSet/adverse-event-causality-assess"/>
  <content value="complete"/>
  <concept>
    <code value="certain"/>
    <display value="Certain"/>
    <definition value="i) Event or laboratory test abnormality, with plausible time relationship to drug intake; ii) Cannot be explained by disease or other drugs; iii) Response to withdrawal plausible (pharmacologically, pathologically); iv) Event definitive pharmacologically or phenomenologically (i.e. an objective and specific medical disorder or a recognized pharmacological phenomenon); or v) Re-challenge satisfactory, if necessary."/>
  </concept>
  <concept>
    <code value="probably-likely"/>
    <display value="Probably/Likely"/>
    <definition value="i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Unlikely to be attributed to disease or other drugs; iii) Response to withdrawal clinically reasonable; or iv) Re-challenge not required."/>
  </concept>
  <concept>
    <code value="possible"/>
    <display value="Possible"/>
    <definition value="i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Could also be explained by disease or other drugs; or iii) Information on drug withdrawal may be lacking or unclear."/>
  </concept>
  <concept>
    <code value="unlikely"/>
    <display value="Unlikely"/>
    <definition value="i) Event or laboratory test abnormality, with a time to drug intake that makes a relationship improbable (but not impossible); or ii) Disease or other drugs provide plausible explanations."/>
  </concept>
  <concept>
    <code value="conditional-classified"/>
    <display value="Conditional/Classified"/>
    <definition value="i) Event or laboratory test abnormality; ii) More data for proper assessment needed; or iii) Additional data under examination."/>
  </concept>
  <concept>
    <code value="unassessable-unclassifiable"/>
    <display value="Unassessable/Unclassifiable"/>
    <definition value="i) Report suggesting an adverse reaction; ii) Cannot be judged because information is insufficient or contradictory; or iii) Data cannot be supplemented or verified."/>
  </concept>
</CodeSystem>